The genitourinary clinical manifestation of estrogen deficiency is:

Explanation

Estrogen deficiency, especially after menopause, can make the vaginal epithelium thin, dry, and less elastic. This characteristic condition is called atrophic vaginitis and is now often included under the broader term genitourinary syndrome of menopause. Recurrent urinary tract infection can also be associated with estrogen deficiency, but atrophic vaginitis is the most direct option listed.